How many institutions own RAPP stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own RAPP shares is 120, representing 106.25% of the company's common stock.

Who are the major shareholders selling Rapport Therapeutics, Inc. Common Stock stock?

CORMORANT ASSET MANAGEMENT, LP, in the last quarter, reduced its stake in RAPP by -5.17% restricting it's holding to 3.03 million shares of worth nearly $91.85M. T. ROWE PRICE INVESTMENT MANAGEMENT, INC. also lessened -12.51% of the RAPP shares from its portfolio, reducing its holding to 619.03 thousand shares of worth $18.78M. MANUFACTURERS LIFE INSURANCE COMPANY, THE also shunned RAPP shares holding by -4.46% last quarter which brought its holding to 78.66 thousand shares worth $2.41M.

Investors who are buying RAPP stock?

As per its latest 13F filing, INVESCO LTD. increased its stake in RAPP by 69.08% in the last quarter. The institutional holder raised its holding to 267.12 thousand shares having worth more than $8.10M. POLAR CAPITAL HOLDINGS PLC also added 7.01% more shares of RAPP to its portfolio, raising its holding to 1 million shares of worth $30.48M. VESTAL POINT CAPITAL, LP also increased its RAPP shares holding by 16.84% which brought its holding to 1.11 million shares worth $33.68M.

RAPP's major insiders: who are they?

The insider with the most stakes in RAPP is Bredt David , Chief Scientific Officer at the company. Additionally, RAPP stock is highly held by Chief Development Officer Yeleswaram Krishnaswamy and Chief Operating Officer Gault Cheryl among others.

Did an insider recently sell RAPP stock?

Company executives, directors, and other insiders own 6.26% percent of Rapport Therapeutics, Inc. Common Stock's stock. Within the last six months, there have been 18 transaction(s) in which RAPP insiders have sold stock, totaling 68.68K shares. Insiders that have sold shares include YELESWARAM KRISHNASWAMY, GAULT CHERYL, and CEESAY ABRAHAM.

Which insider recently purchased RAPP stock?

There have been 0 transaction(s) during the past 6-months in which Rapport Therapeutics, Inc. Common Stock insiders have bought stock, totalling 0 shares

How much of RAPP does insiders own?

Around 4.3M Rapport Therapeutics, Inc. Common Stock shares are held by insiders, which represents about 6.26% of RAPP stock.

Who is the insider with the largest stake?

RAPP Chief Scientific Officer, Bredt David holds the largest portfolio of the company's shares. RAPP shares owned by Bredt total nearly 387.08 thousand.

Which institution holds the most shares in RAPP?

INVESCO LTD. is the largest institutional owner in RAPP which holds 267.12 thousand shares worth $8.10M or 0.7% of the total RAPP shares outstanding followed by CORMORANT ASSET MANAGEMENT, LP with ownership of 3.03 million shares representing 0.8% of the RAPP ownership. ARCH VENTURE MANAGEMENT, LLC is the third largest stakeholder with 3.73 million shares or 0.98% of the ownership worth more than $113.13M.

Is Rapport Therapeutics, Inc. Common Stock stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the RAPP is concerned, it is a stock which is optionable.

Is there a short position on RAPP's shares?

Number of RAPP shares short is 3.15M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding RAPP shares are there?

As of today, 46.11M shares of RAPP are outstanding.

Is there many float in RAPP stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, RAPP has 21.03M shares in float.

RAPP short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for RAPP is 16.77.

Rapport Therapeutics Common Stock (RAPP) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares8.62

Short Percent Of Float20.93

Shares Outstanding46.11M

Shares Float21.03M

Shares Short3.15M

Short Ratio16.77

20.93%

Short % of Float

8.62%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

6.26% Percentage of Shares held by All Insiders

106.25% Percentage of Shares held by All Institutions

113.35% Percentage of Float held by Institutions

120

Number of Institutions Holding Shares

Institutional Ownership

About 106.25% of RAPP shares are held by financial institutions. INVESCO LTD. is the top corporate investor, holding 267.12K shares valued at $8.10M. A 0.7% stake in Rapport Therapeutics, Inc. Common Stock is owned by the company. CORMORANT ASSET MANAGEMENT, LP owns 3.03M shares valued at $91.85M, which translates its holding of 0.8% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	INVESCO LTD.	0.7%	267.12K	8.1M	109.14K	+69.08%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	0.8%	3.03M	91.85M	-165K	-5.17%
Dec 31, 2025	ARCH VENTURE MANAGEMENT, LLC	0.98%	3.73M	113.13M	0	0
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.63%	619.03K	18.78M	-88.48K	-12.51%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.65%	1M	30.48M	65.78K	+7.01%
Dec 31, 2025	VESTAL POINT CAPITAL, LP	2.93%	1.11M	33.68M	160K	+16.84%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	78.66K	2.41M	-3.67K	-4.46%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.02%	83.49K	2.53M	72.16K	+636.87%
Dec 31, 2025	EAM INVESTORS, LLC	0.02%	85.56K	2.6M	-1.72K	-1.97%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	8.79K	266.66K	-1.43K	-13.95%
Dec 31, 2025	TRV GP V, LLC	1.88%	7.14M	216.48M	0	0
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	1.78%	673.92K	20.45M	270K	+66.84%
Dec 31, 2025	SEI INVESTMENTS CO	0%	18.27K	554.25K	10.12K	+124.06%
Dec 31, 2025		0%	17.51K	531.13M	17.51K	+100.00%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0%	16K	485.32K	5.13K	+47.25%
Dec 31, 2025	JPMORGAN CHASE & CO	0%	15.13K	459.01K	5.15K	+51.53%
Dec 31, 2025	ALLIANZ ASSET MANAGEMENT GMBH	0%	13.2K	400.49K	13.2K	+100.00%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0%	12.73K	386K	12.73K	+100.00%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.03%	12.35K	374.79K	5.13K	+71.09%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0%	10.77K	326.64K	3.37K	+45.53%
Dec 31, 2025	CATALYST PRIVATE WEALTH, LLC	0%	10K	303.4K	0	0
Dec 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.01%	44.29K	1.34M	42.81K	+2,896.68%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.01%	46.85K	1.42M	28.6K	+156.71%
Dec 31, 2025	SWISS NATIONAL BANK	0.01%	54.6K	1.66M	54.6K	+100.00%
Dec 31, 2025	CITIGROUP INC	0.01%	56.48K	1.71M	54.71K	+3,091.19%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.02%	66.15K	2.01M	52.81K	+395.83%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.02%	74.08K	2.25M	26.66K	+56.22%
Dec 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.02%	75K	2.28M	0	0
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	10.21K	309.71K	-10.94K	-51.72%
Dec 31, 2025	SWEDBANK AB	0.03%	113.2K	3.43M	113.2K	+100.00%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0%	9.67K	293K	3.41K	+54.40%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.03%	115.19K	3.49M	-21.82K	-15.93%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.53%	201.83K	6.12M	47.65K	+30.91%
Dec 31, 2025	FMR LLC	1.87%	7.11M	215.77M	194.87K	+2.82%
Dec 31, 2025	D. E. SHAW & CO., INC.	0.07%	247.32K	7.5M	247.32K	+100.00%
Dec 31, 2025	NORTHERN TRUST CORP	0.06%	220.82K	6.7M	66.96K	+43.52%
Dec 31, 2025	XTX TOPCO LTD	0.03%	13.06K	396.3K	13.06K	+100.00%
Dec 31, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.05%	178.74K	5.42M	178.74K	+100.00%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.05%	194.2K	5.89M	0	0
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.06%	244.39K	7.41M	41.94K	+20.72%
Dec 31, 2025	JANE STREET GROUP, LLC	0.07%	26K	788.84K	-160.1K	-86.03%
Dec 31, 2025	RHUMBLINE ADVISERS	0.08%	30.73K	932.22K	6.44K	+26.52%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.08%	32.11K	974.19K	18.65K	+138.52%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.09%	34.55K	1.05M	-23.51K	-40.49%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.13%	50.62K	1.54M	29.12K	+135.44%
Dec 31, 2025	BARCLAYS PLC	0.14%	52.48K	1.59M	25.77K	+96.46%
Dec 31, 2025	SIREN, L.L.C.	0.19%	708.47K	21.49M	-345K	-32.75%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.01%	20.88K	633.44K	256	+1.24%
Dec 31, 2025	DEUTSCHE BANK AG\	0.01%	21.54K	653.37K	15.29K	+244.62%
Dec 31, 2025	BAKER BROS. ADVISORS LP	4.08%	1.55M	46.94M	0	0
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0%	9.66K	293.05K	-194.29K	-95.26%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.32%	881.61K	26.75M	-220.78K	-20.03%
Dec 31, 2025	ALLIANCEBERNSTEIN L.P.	2.08%	788.41K	23.92M	-67.21K	-7.86%
Dec 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.09%	34.65K	1.05M	34.65K	+100.00%
Dec 31, 2025	NUVEEN, LLC	0.19%	70.95K	2.15M	49.07K	+224.35%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.25%	952.37K	28.89M	60.11K	+6.74%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.31%	118.81K	3.6M	83.51K	+236.58%
Dec 31, 2025	JOHNSON & JOHNSON	4.7%	1.78M	54.14M	0	0
Dec 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.5%	1.9M	57.78M	-43.17K	-2.22%
Dec 31, 2025	MORGAN STANLEY	0.55%	210.33K	6.38M	-64.24K	-23.40%
Dec 31, 2025	UBS GROUP AG	0.6%	226.36K	6.87M	-331.71K	-59.44%
Dec 31, 2025	PRUDENTIAL FINANCIAL INC	0.67%	254.97K	7.74M	254.97K	+100.00%
Dec 31, 2025	CAPITAL INTERNATIONAL INVESTORS	0.9%	3.4M	103.23M	0	0
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.83%	694.73K	21.08M	161.33K	+30.25%
Dec 31, 2025	SECTORAL ASSET MANAGEMENT INC	0.01%	38.93K	1.18M	-4.56K	-10.48%
Dec 31, 2025	ALPS ADVISORS INC	0.01%	39.14K	1.19M	22.04K	+128.86%
Dec 31, 2025	STATE STREET CORP	1.88%	714.82K	21.69M	343.2K	+92.35%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	22.38K	679.13K	-11.51K	-33.96%
Dec 31, 2025	VANGUARD GROUP INC	4.79%	1.82M	55.15M	191.22K	+11.76%
Dec 31, 2025	BLACKROCK, INC.	6.41%	2.43M	73.78M	863.78K	+55.09%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	7.91%	3M	91.08M	579.9K	+23.94%
Dec 31, 2025	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.04%	16.78K	509.2K	16.78K	+100.00%
Dec 31, 2025	TRV GP VI, LLC	0.26%	969.22K	29.41M	0	0
Dec 31, 2025	ARTIA GLOBAL PARTNERS LP	0.37%	138.51K	4.2M	73.9K	+114.38%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.4%	150K	4.55M	-300K	-66.67%
Dec 31, 2025	SIO CAPITAL MANAGEMENT, LLC	0.49%	185.27K	5.62M	0	0
Dec 31, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	0.66%	250K	7.59M	0	0
Dec 31, 2025	CITADEL ADVISORS LLC	0.04%	16.9K	512.75K	-17.7K	-51.16%
Dec 31, 2025	EVERSEPT PARTNERS, LP	0.16%	59.23K	1.8M	-84.33K	-58.74%
Dec 31, 2025	TREXQUANT INVESTMENT LP	0.17%	62.98K	1.91M	42.46K	+206.93%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.02%	57.15K	1.7M	57.15K	+100.00%
Sep 30, 2025	FORT BAKER CAPITAL MANAGEMENT LP	0.02%	81.64K	2.42M	81.64K	+100.00%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.02%	62.82K	1.87M	62.82K	+100.00%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	0.02%	64.61K	1.92M	64.61K	+100.00%
Sep 30, 2025	WALLEYE CAPITAL LLC	0.02%	69.57K	2.07M	69.57K	+100.00%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.07%	250.59K	7.44M	250.59K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.04%	154.17K	4.58M	154.17K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.13%	450K	13.37M	450K	+100.00%
Sep 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.02%	75K	2.23M	75K	+100.00%
Sep 30, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	0.07%	250K	7.43M	250K	+100.00%
Sep 30, 2025	ARCH VENTURE MANAGEMENT, LLC	1.05%	3.73M	110.74M	0	0
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.01%	50K	1.49M	50K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.04%	153.86K	4.57M	37.58K	+32.32%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.06%	202.45K	6.01M	108.95K	+116.53%
Sep 30, 2025	CITADEL ADVISORS LLC	0.03%	104.88K	3.11M	104.88K	+100.00%
Sep 30, 2025	EAM INVESTORS, LLC	0.02%	87.27K	2.55M	87.27K	+100.00%
Sep 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	82.33K	2.45M	-18.09K	-18.02%
Sep 30, 2025	BIOIMPACT CAPITAL LLC	0.02%	71.81K	2.13M	71.81K	+100.00%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.9%	3.19M	94.82M	251.6K	+8.56%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.04%	157.53K	4.68M	157.53K	+100.00%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.02%	80K	2.38M	80K	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.02%	58.06K	1.72M	45.93K	+378.77%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.01%	47.42K	1.41M	7.32K	+18.25%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.01%	35.3K	1.05M	19.7K	+126.28%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	33.89K	1.01M	32.24K	+1,950.39%
Sep 30, 2025	BARCLAYS PLC	0.01%	26.71K	793.38K	-44.4K	-62.43%
Sep 30, 2025	RHUMBLINE ADVISERS	0.01%	24.29K	721.29K	-663	-2.66%
Sep 30, 2025	NUVEEN, LLC	0.01%	21.87K	649.63K	0	0
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.01%	18.25K	542.03K	18.25K	+100.00%
Sep 30, 2025	ALPS ADVISORS INC	0%	17.1K	507.93K	-2.61K	-13.24%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	16.73K	496K	16.73K	+100.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	13.46K	399.82K	2.2K	+19.48%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0%	13.34K	396.23K	13.34K	+100.00%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0%	11.33K	336.5K	11.33K	+100.00%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0%	10.86K	322.63K	0	0
Sep 30, 2025	CATALYST PRIVATE WEALTH, LLC	0%	10K	297K	0	0
Sep 30, 2025	JPMORGAN CHASE & CO	0%	9.98K	296.52K	-551	-5.23%
Sep 30, 2025	SEI INVESTMENTS CO	0%	8.15K	242.14K	8.15K	+100.00%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0%	7.4K	219.72K	68	+0.93%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	7.3K	216.81K	3.8K	+108.57%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	7.22K	214.43K	5.26K	+268.18%
Sep 30, 2025	BELVEDERE TRADING LLC	0%	3.73K	110.72K	3.73K	+100.00%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0%	6.27K	186K	6.27K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0%	6.25K	185.6K	0	0
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0%	5.25K	155.98K	720	+15.89%
Sep 30, 2025	BRYN MAWR TRUST CO	0%	4.82K	143.21K	4.82K	+100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	2.48K	73.51M	2.48K	+100.00%
Sep 30, 2025	STRS OHIO	0%	2.1K	62.37K	400	+23.53%
Sep 30, 2025	CITIGROUP INC	0%	1.77K	52.57K	-5.28K	-74.90%
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0%	1.48K	44.05K	-310	-17.29%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0%	1.48K	43K	1.48K	+100.00%
Sep 30, 2025	CWM, LLC	0%	1.46K	43K	154	+11.81%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	1.45K	43.18K	1.45K	+100.00%
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	1.41K	41.91K	1	+0.07%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.44%	1.55M	45.95M	997K	+181.24%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.31%	1.1M	32.74M	-423.13K	-27.74%
Sep 30, 2025	SIREN, L.L.C.	0.3%	1.05M	31.29M	675K	+178.35%
Sep 30, 2025	TRV GP VI, LLC	0.27%	969.22K	28.79M	0	0
Sep 30, 2025	VESTAL POINT CAPITAL, LP	0.27%	950K	28.22M	950K	+100.00%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.26%	938.95K	27.89M	938.95K	+100.00%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.25%	892.26K	26.5M	648.38K	+265.86%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.24%	855.62K	25.41M	-299.07K	-25.90%
Sep 30, 2025	UBS GROUP AG	0.16%	558.07K	16.57M	284.57K	+104.04%
Sep 30, 2025	EVERSEPT PARTNERS, LP	0.04%	143.57K	4.26M	143.57K	+100.00%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.04%	137.01K	4.07M	-59.86K	-30.40%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.04%	124.8K	3.71M	124.8K	+100.00%
Sep 30, 2025	TRV GP V, LLC	2.01%	7.14M	211.92M	0	0
Sep 30, 2025	FMR LLC	1.95%	6.92M	205.43M	1.44M	+26.35%
Sep 30, 2025	CAPITAL INTERNATIONAL INVESTORS	0.96%	3.4M	101.06M	800K	+30.74%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.68%	2.42M	71.93M	1.19M	+96.11%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.55%	1.95M	57.84M	-48.02K	-2.41%
Sep 30, 2025	JOHNSON & JOHNSON	0.5%	1.78M	53M	-713.53K	-28.56%
Sep 30, 2025	VANGUARD GROUP INC	0.46%	1.63M	48.31M	519.05K	+46.87%
Sep 30, 2025	BLACKROCK, INC.	0.44%	1.57M	46.57M	348.88K	+28.62%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.2%	707.51K	21.01M	93.69K	+15.26%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.15%	533.4K	15.85M	200.24K	+60.10%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	0.11%	403.92K	12M	403.92K	+100.00%
Sep 30, 2025	STATE STREET CORP	0.1%	371.63K	11.04M	72.92K	+24.41%
Sep 30, 2025	MORGAN STANLEY	0.08%	274.57K	8.15M	205.11K	+295.27%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.06%	203.95K	6.06M	203.95K	+100.00%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.05%	194.2K	5.77M	0	0
Sep 30, 2025	JANE STREET GROUP, LLC	0.05%	186.1K	5.53M	186.1K	+100.00%
Sep 30, 2025	SIO CAPITAL MANAGEMENT, LLC	0.05%	185.27K	5.5M	185.27K	+100.00%
Sep 30, 2025	INVESCO LTD.	0.04%	157.98K	4.69M	157.98K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	0.31%	1.11M	12.59M	-7.93K	-0.71%
Jun 30, 2025	BARCLAYS PLC	0.02%	71.11K	808K	8.41K	+13.42%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.01%	40.1K	455.98K	4.62K	+13.03%
Jun 30, 2025	RHUMBLINE ADVISERS	0.01%	24.95K	283.66K	10.59K	+73.76%
Jun 30, 2025	ACUTA CAPITAL PARTNERS, LLC	0.01%	20K	227.4K	3.6K	+21.95%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.01%	19.74K	224.48K	-14.01K	-41.51%
Jun 30, 2025	ALPS ADVISORS INC	0.01%	19.71K	224.13K	-6.42K	-24.56%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	15.6K	177.37K	15.6K	+100.00%
Jun 30, 2025		0%	12.59K	143.19K	-14.24K	-53.06%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	12.13K	137.88K	4.67K	+62.54%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0%	11.46K	130.32K	11.46K	+100.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0%	11.27K	128.11K	2.3K	+25.65%
Jun 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0%	11.23K	127.69K	11.23K	+100.00%
Jun 30, 2025	CITIGROUP INC	0%	7.05K	80.19K	-8.03K	-53.24%
Jun 30, 2025	NORTHERN TRUST CORP	0.03%	116.27K	1.32M	-11.81K	-9.22%
Jun 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0%	10.86K	123.51K	0	0
Jun 30, 2025	CREATIVE PLANNING	0%	10.6K	120.54K	10.6K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	10.54K	119.78K	-19	-0.18%
Jun 30, 2025	CATALYST PRIVATE WEALTH, LLC	0%	10K	113.7K	0	0
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0%	9.81K	111.55K	-76	-0.77%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.03%	100.42K	1.14M	21.49K	+27.23%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.05%	194.2K	2.21M	0	0
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.06%	196.87K	2.24M	34.05K	+20.91%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.06%	199.64K	2.27M	199.64K	+100.00%
Jun 30, 2025	TRV GP V, LLC	2.01%	7.14M	81.13M	0	0
Jun 30, 2025	FMR LLC	1.54%	5.47M	62.25M	-11.84K	-0.22%
Jun 30, 2025	ARCH VENTURE MANAGEMENT, LLC	1.05%	3.73M	42.43M	0	0
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.83%	2.94M	33.44M	0	0
Jun 30, 2025	CAPITAL INTERNATIONAL INVESTORS	0.73%	2.6M	29.59M	0	0
Jun 30, 2025	JOHNSON & JOHNSON	0.7%	2.5M	28.55M	0	0
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.56%	2M	22.69M	0	0
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.43%	1.53M	17.35M	452.31K	+42.15%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.35%	1.24M	14.04B	-9.28K	-0.75%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.33%	1.15M	13.13B	45.06K	+4.06%
Jun 30, 2025	WOODLINE PARTNERS LP	0.05%	185.03K	2.1M	3K	+1.65%
Jun 30, 2025	MORGAN STANLEY	0.02%	69.46K	789.79M	-7.14K	-9.32%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0%	16.97K	192.97M	16.97K	+100.00%
Jun 30, 2025	BLACKROCK, INC.	0.34%	1.22M	13.86M	51.95K	+4.45%
Jun 30, 2025	TRV GP VI, LLC	0.27%	969.22K	11.02M	0	0
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.17%	613.82K	6.98M	-938.11K	-60.45%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.16%	550.09K	6.25M	550.09K	+100.00%
Jun 30, 2025	NUVEEN, LLC	0.01%	21.87K	248.7K	0	0
Jun 30, 2025	SUMMITTX CAPITAL, L.P.	0%	12.59K	143.19K	-14.24K	-53.06%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.06%	208.91K	2.38M	0	0
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.07%	243.88K	2.77M	40.64K	+19.99%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.01%	24.88K	282.93K	413	+1.69%
Jun 30, 2025	UBS GROUP AG	0.08%	273.51K	3.11M	208.76K	+322.42%
Jun 30, 2025	STATE STREET CORP	0.08%	298.71K	3.4M	107.59K	+56.29%
Jun 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0%	7.33K	83.34K	-7	-0.10%
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0%	8.44K	95.97K	-196	-2.27%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.09%	333.16K	3.79M	17.5K	+5.54%
Jun 30, 2025	SIREN, L.L.C.	0.11%	378.47K	4.3M	0	0
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.04%	131.34K	1.49M	131.34K	+100.00%
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.05%	179.86K	2.05M	179.86K	+100.00%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	0.03%	98.24K	1.12M	-359.32K	-78.53%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.03%	93.5K	1.06M	2.53K	+2.78%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.35%	1.24M	12.48M	-7.83K	-0.63%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.01%	33.76K	338.58K	33.76K	+100.00%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	0.83%	2.94M	29.5M	0	0
Mar 31, 2025	MORGAN STANLEY	0.02%	76.6K	768.34K	53.97K	+238.42%
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	78.93K	791.68K	1.66K	+2.14%
Mar 31, 2025	STATE STREET CORP	0.05%	191.12K	1.92M	23.58K	+14.08%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0%	12K	120.36K	12K	+100.00%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.06%	194.2K	1.95M	194.2K	+100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.09%	315.66K	3.17M	104.99K	+49.83%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.57%	2M	20.02M	0	0
Mar 31, 2025	JOHNSON & JOHNSON	0.71%	2.5M	25.06M	0	0
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.44%	1.55M	15.57M	-85.01K	-5.19%
Mar 31, 2025	FMR LLC	1.56%	5.49M	55.03M	0	0
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0%	8.97K	89.94K	4.14K	+85.88%
Mar 31, 2025	NORTHERN TRUST CORP	0.04%	128.08K	1.28M	55.26K	+75.88%
Mar 31, 2025	DEEP TRACK CAPITAL, LP	0.13%	457.56K	4.59M	457.56K	+100.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.3%	1.07M	10.77M	-70.18K	-6.14%
Mar 31, 2025	XTX TOPCO LTD	0%	15.44K	154.88K	15.44K	+100.00%
Mar 31, 2025	ACUTA CAPITAL PARTNERS, LLC	0%	16.4K	164.49K	0	0
Mar 31, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	29.94K	300.29K	21.37K	+249.31%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.05%	162.82K	1.63M	-15.09K	-8.48%
Mar 31, 2025	CITIGROUP INC	0%	15.09K	151.3K	5.51K	+57.51%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.06%	203.24K	2.04M	203.24K	+100.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	7.46K	74.83K	883	+13.42%
Mar 31, 2025	COREBRIDGE FINANCIAL, INC.	0%	8.27K	82.96K	3.65K	+79.10%
Mar 31, 2025	SWISS NATIONAL BANK	0.01%	31.9K	319.96K	13.9K	+77.22%
Mar 31, 2025	CITADEL ADVISORS LLC	0.07%	249.41K	2.5M	-238.04K	-48.83%
Mar 31, 2025	CAPITAL INTERNATIONAL INVESTORS	0.74%	2.6M	26.1M	0	0
Mar 31, 2025	VANGUARD GROUP INC	0.32%	1.12M	11.19M	559.95K	+100.81%
Mar 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0%	8.64K	86.63K	8.64K	+100.00%
Mar 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0%	10.86K	108.96K	5.15K	+90.25%
Mar 31, 2025	BARCLAYS PLC	0.02%	62.7K	629K	44.2K	+238.95%
Mar 31, 2025	UBS GROUP AG	0.02%	64.75K	649.41K	43.42K	+203.58%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.31%	1.11M	11.13M	11.21K	+1.02%
Mar 31, 2025	JUMP FINANCIAL, LLC	0%	13.76K	138.01K	13.76K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	0.33%	1.17M	11.71M	410.71K	+54.29%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0%	9.89K	99.17K	4.58K	+86.37%
Mar 31, 2025	CATALYST PRIVATE WEALTH, LLC	0%	10K	100.3K	10K	+100.00%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0%	10.3K	103.27K	773	+8.12%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	10.55K	105.86K	3.38K	+47.20%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.01%	24.47K	245.44K	24.47K	+100.00%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.01%	35.48K	355.88K	15.51K	+77.69%
Mar 31, 2025	RHUMBLINE ADVISERS	0%	14.36K	144.01K	4.11K	+40.09%
Mar 31, 2025		0.01%	21.87K	219.39K	21.87K	+100.00%
Mar 31, 2025	ALPS ADVISORS INC	0.01%	26.13K	262.06K	-3.45K	-11.67%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.03%	90.97K	912.41K	17.46K	+23.75%
Mar 31, 2025	WOODLINE PARTNERS LP	0.05%	182.03K	1.83M	498	+0.27%
Mar 31, 2025	SIREN, L.L.C.	0.11%	378.47K	3.8M	-5.73K	-1.49%
Mar 31, 2025	ARCH VENTURE MANAGEMENT, LLC	1.06%	3.73M	37.55M	0	0

Insiders

Among the RAPP insiders holding of 6.26% of the stake in company, BREDT DAVID, Chief Scientific Officer, holds the largest shares of 387.08K. YELESWARAM KRISHNASWAMY, Chief Development Officer, is the second largest RAPP insider with ownership of 266.65K shares. GAULT CHERYL, Chief Operating Officer, stands third with possession of 159.91K shares of that stake.

Insiders	Designation	Shares Held
BREDT DAVID	Chief Scientific Officer	387.08K
YELESWARAM KRISHNASWAMY	Chief Development Officer	266.65K
GAULT CHERYL	Chief Operating Officer	159.91K
PAUL STEVEN M	director	28.28K
CEESAY ABRAHAM	Chief Executive Officer	20.73K
HUBER REID M	director	20.4K
IGNELZI TROY A.	Chief Financial Officer	10K
YOUNG WENDY B.	director	9.5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Apr 14, 2026	YELESWARAM KRISHNASWAMY	SALE	35.08	10.2K	357.8K	266.65K
Apr 13, 2026	YELESWARAM KRISHNASWAMY	SALE	34.97	9.17K	320.54K	276.85K
Apr 10, 2026	YELESWARAM KRISHNASWAMY	SALE	34.98	500	17.49K	286.02K
Apr 08, 2026	YELESWARAM KRISHNASWAMY	SALE	34.90	360	12.56K	286.52K
Mar 30, 2026	GAULT CHERYL	SALE	28.55	2.84K	81.06K	159.91K
Mar 25, 2026	YELESWARAM KRISHNASWAMY	SALE	29.99	10.12K	303.35K	286.88K
Mar 05, 2026	GAULT CHERYL	SALE	28.93	2.01K	58.27K	169.91K
Feb 18, 2026	CEESAY ABRAHAM	SALE	29.80	2.1K	62.57K	20.73K
Feb 17, 2026	BREDT DAVID	SALE	29.59	2.2K	65.11K	387.08K
Jan 20, 2026	CEESAY ABRAHAM	SALE	26.11	5.08K	132.74K	25.81K
Jan 15, 2026	BREDT DAVID	SALE	27.40	200	5.48K	395.58K
Dec 31, 2025	YELESWARAM KRISHNASWAMY	SALE	30.05	2.84K	85.34K	296.99K
Dec 31, 2025	BREDT DAVID	SALE	30.05	6.57K	197.34K	404.08K
Dec 17, 2025	CEESAY ABRAHAM	SALE	31.04	515	15.99K	30.9K
Dec 15, 2025	BREDT DAVID	SALE	30.68	796	24.42K	392.64K
Nov 26, 2025	GAULT CHERYL	SALE	30.10	5K	150.49K	171.93K
Nov 17, 2025	CEESAY ABRAHAM	SALE	25.44	2.84K	72.27K	35.98K
Nov 17, 2025	BREDT DAVID	SALE	25.39	5.34K	135.7K	401.14K
Oct 15, 2025	CEESAY ABRAHAM	SALE	26.17	755	19.76K	41.06K
Oct 15, 2025	BREDT DAVID	SALE	26.16	1.08K	28.31K	409.64K
Sep 17, 2025	CEESAY ABRAHAM	SALE	27.04	700	18.93K	46.14K
Sep 15, 2025	BREDT DAVID	SALE	24.66	3.4K	83.89K	418.14K
Sep 12, 2025	HUBER REID M	PURCHASE	24.48	20.4K	499.37K	20.4K
Sep 12, 2025	PAUL STEVEN M	PURCHASE	24.50	28.28K	692.95K	28.28K
Sep 11, 2025	YOUNG WENDY B.	PURCHASE	22.60	3.5K	79.1K	9.5K
Sep 08, 2025	GAULT CHERYL	SALE	38.33	5K	191.65K	171.93K
Aug 15, 2025	BREDT DAVID	SALE	15.79	200	3.16K	426.64K
Jul 15, 2025	BREDT DAVID	SALE	14.00	8.5K	118.96K	435.14K
Jun 16, 2025	BREDT DAVID	SALE	11.00	8.5K	93.52K	443.64K
May 15, 2025	BREDT DAVID	SALE	9.56	8.5K	81.26K	452.14K
Apr 15, 2025	BREDT DAVID	SALE	9.57	8.5K	81.31K	460.64K
Mar 14, 2025	BREDT DAVID	SALE	10.85	8.5K	92.21K	469.14K
Mar 13, 2025	IGNELZI TROY A.	PURCHASE	9.98	100	998	10K
Mar 12, 2025	YOUNG WENDY B.	PURCHASE	10.21	6K	61.25K	6K
Mar 12, 2025	IGNELZI TROY A.	PURCHASE	10.10	9.9K	99.99K	9.9K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES68.68K18

NET SHARES-68.68K18

SHARES HELD4.3M18

% NET SHARES-101.6%0%

Frequently Asked Questions